The LRRFIP1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GCF2, and LRRFIP1. This antibody recognizes Human antigen. The LRRFIP1 Antibody has been validated for the following applications: ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
LRRFIP1 Antibody: LRRFIP1, also known as GC-binding factor 2 (GCF2), is a 738 amino acid transcriptional repressor that mainly plays a cytoskeletal role. It is primarily localized in the cytoplasm and preferentially binds to GC-rich dsDNA, but will also bind directly to dsRNA as well. The RNA binding domain encompasses a lysine-rich motif. LRRFIP1 interacts with the mammalian Flightless I (Fli-I) and is a key component in the cytoskeletal regulation of platelet function. LRRFIP1 and the related protein LRRFIP2 may modulate canonical WNT signaling and mediate the IRF3-induced production of type I interferon via a beta-catenin-dependent pathway